DifferentialvarGene Expression in Children with Malaria and Antidromic Effects on Host Gene Expression

Differential var gene expression in children with malaria and antidromic effects on host gene expression.

Among 62 children with mild malaria, cerebral malaria, or severe malarial anemia, we analyzed the transcription of different var gene types. There was no difference in parasitemia level or body temperature between groups. However, a significantly different expression pattern was observed in children with cerebral malaria, compared with that in patients in the other 2 groups: children with cereb...

Interleukin-17 Gene Expression and Serum Levels in Children with Severe Asthma

Background: IL-17 is a major cytokine player in T cell mediated leukocyte associated inflammation. IL-17 is also recognized to participate in the pathophysiology of asthma. Objective: To determine the role of IL-17 in predicting severe asthma. Methods: We obtained serum samples from asthmatic children under the age of 5-year in three different groups of mild (n=33), moderate (n=28) and severe (...

Effects of Aerobic Training on mTORC1 Gene Expression in Male Wistar Rats with Type 2 Diabetes

Objective: Although type 2 diabetes is a multifactorial illness, one of the major risk factors is the prevalence of obesity.In this context, recent genetic studies on diabetics or pre-diabetics, have shown that some of  the newly-known genes make the conditions for type 2 diabetes even in the absence of obesity. One of these genes is called mTORC1, which plays an important role in the synt...

investigation smta mutant gene expression in e. coli host

The effects of herbal plants on Mucin 2 gene expression and performance in ascetic broilers

The mucus layer plays an important role as an intermediate for the protection of the gut against acidic chyme, digestive enzymes, and pathogens; in addition, it acts as a lubricant and facilitator of nutrient transportation. Phytogenic compounds seem to promote intestinal mucus production. OBJECTIVES: The current study was conducted to investigate the effects of low and high levels of energy an...